The World Lupus Federation (WLF) is a coalition of lupus patient organizations, united to improve the quality of life for all people living with lupus.

The World Lupus Federation facilitates collaborative efforts among nonprofit lupus organizations worldwide and enhances their capacity to engage in coordinated awareness, education and advocacy initiatives. Through the coordinated efforts of its global affiliates, the WLF works to create greater awareness and understanding of lupus, provides education and services to people living with the disease, and advocates on their behalf.